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The APC of screening in the periods 2007-2011 and 2011-2018 were 16.6 and 2.9%, respectively (p 0.001). The prevalence of GDM increased in this period of eleven years along with the prevalence of obesity. The prevalence of GDM increased in this period of eleven years along with the prevalence of obesity. One of the devastating consequences of monoclonal gammopathies is the development of end-stage kidney disease, which can be prevented with an early diagnosis. Renal involvement can be secondary to saturation of paraproteins with i