https://www.selleckchem.com/pr....oducts/as1517499.htm
Glucocorticoids are widely used to treat various diseases including rheumatoid arthritis (RA); however, one of the most frequent and severe adverse effects is glucocorticoid-induced osteoporosis (GIOP). Iguratimod (IGU) is a novel conventional synthetic disease-modifying anti-rheumatic drug developed in Japan. The aim of this study is to investigate the effects of IGU on glucocorticoid-induced disorder of bone metabolism in vitro. In osteoclastogenesis of mouse bone marrow-derived cells, tartrate-resistant acid phosphatase staining, r
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