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ADHD Medication - Ritalin (Methylphenidate) Ritalin (methylphenidate) increases the levels of two brain chemicals that regulate focus and movement. It is one of the most common medications for children with ADHD. It also helps adults concentrate better and less twitchy. There are people who combine Ritalin with other ADHD treatments, such as behavioral therapy. However, certain medications can affect the medication. For instance, one shouldn't use it with monoamine oxidese inhibitors such as isocarboxazid