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Lipids tend to be amphiphilic molecules that self-assemble to create biological membranes. Lots and lots of lipid species coexist into the cell and, once combined, define organelle identity. Because of recent progress in lipidomic analysis, we now know how lipid composition is finely tuned in various subcellular areas. Along side lipid synthesis, renovating and flip-flop, lipid transfer is just one of the energetic procedures that