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© Georg Thieme Verlag KG Stuttgart · New York.Androgens play a pivotal role in non-reproductive body organs for instance the renal, heart, liver, and pancreas. As androgen receptors tend to be expressed in pancreatic and liver cells, extra testosterone can lead to hypersecretion of insulin and fetuin-A, a protein stated in the liver. The expression of fetuin-A, an all-natural inhibitor of tyrosine kinase task in muscle and liver, leads to insulin resistance. In addition, insulin a