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0 ± 12.5 years; 44% men). MACEs occurred in 51 (0.4%) patients. After propensity score weighting, the risk of MACEs was significantly greater with IL12/23 (HRw 2.0, 95%CI 1.3-3. and IL17 (HRw 1.9, 95%CI 1.2-3. inhibitors than TNF inhibitors, with no significant increased risk with apremilast (HRw 1.3, 95%CI 0.8-2.2). Similar results were observed with the Fine-Gray competing-risks survival model. Analysis of a large database revealed a small overall number of MACEs, and the risk of MACEs was greater for PsA new users of IL12/23 and