https://tacrolimusinhibitor.co....m/examining-signific
Tumor hypoxia seems is the main bottleneck of photodynamic therapy (PDT) to clinical transformation. Distinct from traditional O2 distribution approaches, here we describe a cutting-edge binary photodynamic O2-economizer (PDOE) tactic to reverse hypoxia-driven resistance by creating a superoxide radical (O2•-) generator focusing on mitochondria respiration, termed SORgenTAM. This PDOE system has the capacity to stop intracellular O2 usage and down-regulate HIF