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However, probiotic administration prevented the ferroptotic symptoms induced by PFBS, further highlighting the beneficial effects of the probiotic on the host. In PFBS-exposed livers, high levels of bile acid metabolites (e.g., taurochenodeoxycholic acid) accumulated, implying the induction of cholestasis. Notably, probiotic addition recovered the metabolomic homeostasis under PFBS stress, probably resulting from the activation of detoxification pathways based on the pentose and glucuronate interconversion. Overall, the present study pr