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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medication. Finding the right medication dosage and dose isn't always easy. Stimulants: These medications are used to treat both hyperactivity and inattention. They work by increasing levels of chemicals that send messages between nerve cells. They are administered several times per day and begin working in less than an hour. Stimulants Stimulants are the primary medication most doctors