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Taken together, the merchandise of LcLAR1 depended from the substrates, which unveiled the substrate variety of LcLAR1. Our research provides new ideas in to the flavonoid pathway, particularly the part of LAR.A double functionalization of vicinal sp3 C-H bonds was developed, wherein a β amine and γ iodide are integrated onto an aliphatic alcohol in one operation. This approach is enabled by an imidate radical chaper