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Two tetraphenylethene-based tetracationic cyclophanes 1 and 2 were synthesized via a one-step SN2 reaction without using any template. Based on the fluorescence and rotational conformation of the tetraphenylethene units, these water-soluble cyclophanes exhibited adaptive chirality with dual responses of turn-on fluorescence and induced circular dichroism when combined with nucleotides and DNA in water.Many natural products have demonstrated functionality as novel, green sorbents for organic compounds. However, only limited reports exist