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05). At 48h time point, although 8mg/L and 16mg/L OW showed statistically significant reduction in compare to 0h time point, 2mg/L and 4mg/L OW groups didn't experience any statistically significant difference (p 0.05). Considering our findings, due to ozonated water's induced a higher proliferation rate of dental pulp cells, indicating their biocompatibility and a possible adjuvant on irrigating agent in regenerative endodontic procedures. Considering our findings, due to ozonated water's induced a higher proliferation rate of den