https://www.selleckchem.com/pr....oducts/deferoxamine-
Decreased FADS2 expression at both mRNA and protein levels was confirmed in surgical specimens. The restoration of FADS2 expression, which allows for the endogenous conversion of n-3 fatty acids into proresolving lipid mediators, resulted in a significant reduction in proinflammatory macrophage infiltration and attenuated expression of inflammatory cytokines or adipokines. CONCLUSIONS These findings indicate that impaired fatty acid desaturation and lipid mediator imbalance within mesenteric adipose tissue contributes to c
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