https://www.selleckchem.com/pr....oducts/exarafenib.ht
014] APOE4 carriers had smaller hippocampal volume than non-carriers at relatively high cognitive activity state (p = 0.004), but not at relatively low cognitive activity condition (p = 0.937). Midlife physical activity significantly moderated the effect of Aβ retention, which was closely related to APOE4, on AD-signature region cerebral glucose metabolism [AD-CM; B (SE) = 0.004 (0.002), t = 2.030, p = 0.043] higher Aβ accumulation was associated with lower AD-CM in relatively low physical activity condition (p less then 0.001), wher