https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
BACKGROUND Cancer is the second leading cause of mortality worldwide. Despite of several advances made in the treatment strategies, cure for cancer remains still a challenge. Currently used treatment modalities pose several side effects and remain ineffective in the later stages. Thiazolidinediones (TZDs) have been shown to possess anti-cancer activity in several in vitro models. OBJECTIVES The objectives of this study were to assess the effect of novel synthesized thiazolidinedione derivatives on three selected cancer cel