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05). The best cut-off for the diagnosis of diabetes insipidus, was the combination of 400 mosmol/kg in urine and 302 mosmol/kg in serum. With this cut-off a sensitivity of 90% and specificity of 98% was achieved. After 12 h fasting our proposed cut off clearly differentiated between diabetes insipidus, and non-diabetes insipidus suggesting a possibility to considerably reduce the duration of the fluid deprivation test. After 12 h fasting our proposed cut off clearly differentiated between diabetes insipidus, and non-diabetes