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Methionine, choline, and cysteine were additionally associated with the mean methylation of the entire (β = 9.5 (1.0-18., p = 0.04; β = 1.6 (0.4-3., p = 0.04; and β = 4.3 (0.9-7.7), p = 0.02, respectively). Associations of the SLEDAI with hypomethylation were confirmed for CpG17 (β=-32.6 (-60.6 to -4.6), p = 0.04) and CpG22 (β=-38.3 (-61.2 to -15.4), p = 0.004), but not the mean methylation of . Dietary products with the highest impact on methylation included meat, ice cream, white bread, and cooked potatoes. Dietary methyl donors