https://www.selleckchem.com/pr....oducts/zinc05007751.
We also detected T cells expressing OSM in the giant papillae. In addition, HconEpiCs showed surface expression of OSMRβ. Recombinant human OSM strongly activated both STAT1 and STAT3 in HconEpiCs and induced various tissue remodeling-related genes, including MMP-1, MMP-3, IL-24, IL-20, serpinB3, S100A7, tenascin C, and SOCS3. Our results suggest that OSM is one of the key molecules involved in remodeling of giant papillae in VKC. Our results suggest that OSM is one of the key molecules involved in remodeling of giant papillae in V
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