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RBD- and HR-based nanoparticles hence provide a promising vaccination approach against SARS-CoV-2 along with other coronaviruses.As the use of transcatheter aortic device implantation (TAVI) expands to varying patient populations, impacting the landscape of surgical aortic valve replacement (SAVR), this study sought to evaluate volume and performance trends of aortic valve replacement (AVR) in the United States during