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Understanding factors involved in the rate of C-peptide decline is needed to tailor therapies for type 1 diabetes (T1D). Evaluate factors associated with rate of C-peptide decline after a T1D diagnosis in young children. Observational study. Academic centers. A total of 57 participants from the Environmental Determinants of Diabetes in the Young (TEDDY) study who were enrolled at 3 months of age and followed until T1D, and 56 age-matched children diagnosed with T1D in the community. A mixed meal tolerance test was used to measure the area
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