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Primary cultured rat and human hepatocytes were considered to be useful for the evaluation of effects of the benzimidazole compounds on their inducibility and inhibitory activities of cytochrome P450 forms.Quercetin and gallic acid are phytochemicals with interesting pharmacological properties. We herein investigated the protective effect of quercetin (QUE) in comparison with gallic acid (GAL) against exogenously-induced oxidative damage in rats' kidney and human embryonic kidney (HEK-293) cell lines. Adult Wistar rats were treated with