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01). A significant decrease in pain was noticed between inclusion and 13 weeks in the UPA group (p 0.01). At 6 months, there was no significant difference in PBAC score or pain between groups. No serious adverse event was recorded. UPA could be an interesting option for treatment of abnormal uterine bleeding related to adenomyosis in women wishing to preserve their fertility. UPA could be an interesting option for treatment of abnormal uterine bleeding related to adenomyosis in women wishing to preserve their fertility. Acute dysme