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Despite its relatively long history, open-channel hydrodynamic chromatography (OC-HDC) still represents a niche technique for determining the size distribution of particle suspensions. Practical limitations of this separation method ultimately arise from the low eluent velocity that is necessary to contain the adverse increase of analyte bandwidth caused by Taylor-Aris dispersion. Because of the micrometric size of the channel cross section, the low eluent velocity translates into order of pL-per-minute flow rates, which introduce a cha