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8 ± 1.4% and 42.2 ± 2.6% at GSE with 50 μg/mL and 100 μg/mL vs. 21.03 ± 1.10%, control). Pre-treatment with salubrinal, an inhibitor of ER stress, effectively attenuated cell cycle arrest induced by GSE. Our findings provide new evidence that GSE suppresses growth of cancer cells through activating the ER stress pathway. The GSE may be clinically applied in the prevention and/or treatment of cancer. Our findings provide new evidence that GSE suppresses growth of cancer cells in vitro through activating the ER stress pathway. The GSE may
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