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A systematic review and meta-analysis was conducted to summarise studies conducted on the effects ofartichoke supplementation on liver enzymes. Suitable studies were detected by searching online databases, including Medline, Embase, Cochrane Library, and Scopus databases, until 05 June 2021. As liver enzymes were reported in different units, standardised mean differences (SMD) were used and data were pooled using a random-effects model. Heterogeneity, publication bias, and sensitivity analysis were also assessed. Pooled analysis, of eigh