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ve in reducing the procedure-associated pain during MAL-cPDT for the treatment of AK lesions. V.BACKGROUND This study aimed to evaluate the reduction of halitosis when using antimicrobial photodynamic therapy (aPDT) withBixa orellana extract and blue light-emitting diode (LED). METHODS Forty-four UNINOVE students or employees with a diagnosis of sulfide (H2S) ≥ 112 ppb in gas chromatography were selected. The patients were randomly divided in groups Group 1 (n = 15) aPDT with annatto and LED; Group 2 (n = 14) tongue scraping; Group 3 (n = 15) tongue scrapin