https://www.selleckchem.com/pr....oducts/daurisoline.h
BACKGROUND Retinoblastoma (R is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes (DEGs) between an etoposide drug-resistant subline (Y79/EDR) and parental Y79 cells. METHODS To test whether Y79/EDR cells showed resistance to antineoplastic agents for RB, we treated the cells with etoposide, carbop
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