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75 to 4.92). Significant moderation was also present between past-year methamphetamine use, risk of STI, and substance use treatment. In this analysis, we demonstrated a strong relationship between methamphetamine use and risk of STIs that differed based on receipt of substance use treatment. These findings suggested that integrated STI and substance use treatment programmes may yield substantial public health benefits. In this analysis, we demonstrated a strong relationship between methamphetamine use and risk of STIs that diff