https://www.selleckchem.com/pr....oducts/cobimetinib-g
A complex anal fistula is a challenging disease to manage. To review the experience and insights gained in treating a large cohort of patients at an exclusive fistula center. Anal fistulas operated on by a single surgeon over 14 years were analyzed. Preoperative magnetic resonance imaging was done in all patients. Four procedures were performed fistulotomy; two novel sphincter-saving procedures, proximal superficial cauterization of the internal opening and regular emptying and curettage of fistula tracts (PERFACT) a