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Objectives The gold-standard COVID-19 analysis relies on detecting SARS-CoV-2 utilizing RNA purification and one-step retrotranscription and quantitative PCR (RT-qPCR). Based on the urgent importance of high-throughput testing, we tested the performance of three alternate, simple and inexpensive protocols to quickly detect SARS-CoV-2, bypassing the long and tedious RNA extraction action and decreasing the time and energy to viral recognition. Techniques We evaluated three