https://www.selleckchem.com/pr....oducts/Tipifarnib(R1
Sleep and wake are opposing behavioral states controlled by the activity of specific neurons that need to be located and mapped. To better understand how a waking brain falls asleep it is necessary to identify activity of individual phenotype-specific neurons, especially neurons that anticipate sleep onset. In freely-behaving mice, we used microendoscopy to monitor calcium (Ca 2+) fluorescence in individual hypothalamic neurons expressing the vesicular GABA transporter (vGAT), a validated marker of GABA neurons. vGAT-Cre mic