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Specimens addressed with DNase+melittin revealed an even more significant decrease in the CFUs, eDNA level, and biofilm formation rate compared to those addressed just with melittin or DNase (p less then 0.05). CLSM analysis demonstrated DNase+melittin treatment significantly decreased the amount of biofilms and extracellular polymeric material compared to either treatment alone (p less then 0.05). FE-SEM photos revealed increased amount of biofilm disruption in specimens that obtai