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hese biomarkers. Gender differences have been noted in studies linking blood pressure to all-cause dementia, and the two most common forms of dementia Alzheimer's disease (AD) and vascular dementia (VaD). However, how gender modifies the relationship between blood pressure and dementia remains unclear. To review evidence for a gender modifying effect on the link between blood pressure and all-cause dementia. A systematic review was conducted according to PRISMA guidelines. Sixteen out of 256 reviewed articles met inclusion criteria. For women, higher midlif