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agariphila did not catalyze transglycosylation in our lab parameters. The primary aim of this study was to investigate the pharmacokinetics of F-DCFPyL, an F-labeled PSMA-based ligand, and to explore the utility of early time point positron emission tomography (PET) imaging extracted from PET data to distinguish malignant primary prostate from benign prostate tissue. Ten consecutive patients with biopsy-proven high-risk prostate cancer underwent a dynamic F-DCFPyL PET/CT scan of the pelvis for the first 45 min post-injection (p.i.) foll