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We also discuss just how preliminary researches concerning heregulin signaling via HER3-HER2 axis and HER2-overexpressing cancer of the breast cells not only discovered a mechanistic role of PAK1 in cancer of the breast pathobiology but in addition acted as a bridge in creating a broader cancer study curiosity about various other PAK members of the family and cancer types and catalyzed setting up the part of PAKs in real human cancer, at-large. In addition, growt