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States stand to realize substantial savings from a potential AD treatment. A state's health system preparedness to handle the large number of patients will influence the actual magnitude of the savings and how fast they will accrue. As cerebrospinal fluid (CSF) neurofilament light protein (NfL) and the CSF/serum albumin ratio (Q ) are used in the clinical routine, the impact of demographic factors on these biomarkers is important to understand. Participants were derived from two Swedish samples the population-based H70 Study (n = 308, a