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These patients should be carefully evaluated for vitamin D deficiency. More studies are required to further investigate the association between JAK2 and vitamin D. © Penerbit Universiti Sains Malaysia, 2020.Introduction The aim of the current study is to evaluate the antihyperlipidemic and anti-oxidative effects of hydro-alcoholic extract of marjoram (HAEM) in rats fed with a high-fat diet (HFD). Methods In the experimental study, the rats were randomly divided into four groups of five rats in each and fed with high-fat diet for 12 we