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Rats had been divided into control, wogonin, kainate, and wogonin-pretreated kainate teams. The rat model of TLE was induced by unilateral intrahippocampal injection of 0.4 ug/ul of kainate. The results revealed that the cognitive purpose in TLE rats had been substantially impaired, and wogonin treatment enhanced intellectual function in the Morris liquid maze (MWM). H E staining and TUNEL staining showed obvious damage when you look at t