https://www.selleckchem.com/pr....oducts/Irinotecan-cp
Nuclear envelope budding is a recently described phenomenon wherein large macromolecular complexes are packaged inside the nucleus and extruded through the nuclear membranes. While a general outline of the cellular events occurring during NE-budding is now in place, little is yet known about the molecular machinery and mechanisms underlying the physical aspects of NE-bud formation. Using a multidisciplinary approach, we identify Wash, its regulatory complex (SHRC), capping protein, and Arp2/3 as new molecular components involv