https://www.selleckchem.com/pr....oducts/epacadostat-i
(Ph-like) ALL is a subset of leukemia which has a gene expression profile similar to Ph+disease, but without the presence of BCR-ABL1 translocation. We reported an exceptional case of a child with relapsed Ph-like ALL with IKZF1 gene deletion treated with high-dose ruxolitinib as monotherapy, after multi-agent chemotherapy. He remains in continued MRD-negative leukemia remission with full donor chimerism at 12months post-HSCT. The circumstance that makes our case featured is the usage of ruxolitinib as monotherapy. This r
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