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004) or patients with primary tumor burden beyond the Milan criteria (P = .004). Multivariate analysis showed that treatment allocation was identified as an independent prognostic factor for PRS. CONCLUSION Compared with RFA, RHR provided a survival advantage for recurrent HCC, especially for patients who relapsed within 2 years and those with primary tumor burden beyond the Milan criteria. © 2020 The Authors. Cancer Medicine published by John Wiley Sons Ltd.The rising concerns of the recurrence and bone deficiency in surgical treatm