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The data support proteusins as an abundant resource of chemical scaffolds, new maturation enzymes, and bioactivities. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.There is promising desire for the tacrolimus metabolic process rate since it is connected to outcomes after transplantation (1-7). We and others propose the concentration-to-dose (C/D) proportion as an easy surrogate for the individual tacrolimus (Tac) metabolic rate rate (5;8;9). Recently, Jouve et al. sho