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Conclusions Although the single inhibitory effects of gabapentinoids on inflammatory and nociceptive responses are moderate, a combination of both effects might provide an explanation for the proposed function of these substances as an adjuvant for the reduction of neuropathic pain.With recent technological advancement, a major shift in the lifestyle of individuals has been observed. This change is more evident in youth in terms of sleep pattern changes and socialization. It is therefore important to assess the quality of life in this