https://www.selleckchem.com/pr....oducts/bay-87-2243.h
Rationale Hypokalemia occurs in up to 20% of hospitalized patients, and is associated with increased incidence of ventricular and atrial fibrillation. It is unclear whether these differing types of arrhythmia result from direct and perhaps distinct effects of hypokalemia on cardiomyocytes. Objective To investigate pro-arrhythmic mechanisms of hypokalemia in ventricular and atrial myocytes. Methods and Results Experiments were performed in isolated rat myocytes exposed to simulated hypokalemia conditions (reduction of extracellular [
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