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CONCLUSIONS We encountered a rare case of SC of the breast with predominant CIS.Pediatric brain tumors are the leading cause of childhood cancer mortality with medulloblastoma (M representing the most frequent malignant tumor. Although standardization of therapy resulted in a 2-fold reduction in mortality in patients with MB by 2002, it became clear that further improvements in clinical outcome would require a deeper understanding of the biology of MB. Employing the four main molecular MB subgroups (Wnt, Shh, Group 3 and Group 4), a
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