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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a range of issues for adults. This includes issues with work, relationships and mental health. Adults suffering from untreated ADHD typically suffer from low self-esteem, as well as have a negative outlook on the world. This can make them feel as if they're failing at home and work. Lack of Focus Having trouble staying focused at times is normal particularly after a l