https://www.selleckchem.com/pr....oducts/lonafarnib-sc
Tapentadol has relatively less effect on mu-opioid receptors compared with other opioids. This has the potential to reduce the occurrence of gastrointestinal (GI) adverse drug events (ADEs). To compare the GI ADEs during hospitalization between tapentadol immediate release (IR) and oxycodone IR following orthopedic surgeries. Retrospective cohort study. A major metropolitan tertiary referral hospital in Australia. Data for adult orthopedic surgery patients receiving postoperative tapentadol IR or oxycodone IR during hospital