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Life can be well represented by this hierarchical snapshot of its structure, although a more comprehensive view must invoke the characteristics of living, and not just life per se. V.Psoriasis is a chronic inflammatory disease involving multiple organ systems and affecting approximately 2% of the world's population. In this guideline, we focus the discussion on systemic, non-biologic medications for the treatment of this disease. We provide a detailed discussion of efficacy and safety for the most commonly used medications-including metho