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Information Sources We followed the Preferred Reporting products for Systematic Reviews and Meta-analyses tips. We searched PubMed, Embase, OvidSP, CINAHL, and Cochrane Library from January 1, 1966, to July 1, 2018. This research had been registered when you look at the Overseas possible enroll of organized Reviews (CRD42018109314). Study Selection We included randomized studies. Included researches need excluded recognizable factors. Corticosteroids will need to have