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During these structures, the base-labile protecting group 9-fluorenylmethyloxycarbonyl (Fmoc) was paired to your p-toluensulfonyl (tosyl, Ts) or acid-labile tert-butyloxycarbonyl (Boc) moieties. The synthetic approach to protected l-Dap methyl esters uses appropriately masked 2,3-diaminopropanols, that are gotten via reductive amination of an aldehyde prepared from the commercial amino acid Nα-Fmoc-O-tert-butyl-d-serine, used given that starting product. Reductive amination is completed with major am